The AVA Interchange ICC Profile is a device-independent colour space that does not depend on or relate to the characteristics of a native colour space for a particular print scenario (printer, substrate, ink type), but rather contains all possible colours for those scenarios (pretty much). Due to this fact, it serves only as a PCS (Profile Connection Space) as a concrete method of handing over (Interchanging) image colour values to the printer's native colour space (for final conversion and print). AVA's Interchange Profile (D50 and D65) have been specially configured to perform this task with PrintFactory's colour management. 

Device independent colour spaces such as Adobe1998, eciRGB and Iso Coated (which may sound more familiar to you) are performing pretty much the same task. 

Visual below shows a Zimmer cotton reactive profile sat within the Interchange colourspace